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From Lab to Real World: Translating Wearable Sensor Data into Clinical Practice for Stroke Rehabilitation
Mohamed Elsayed, BA, Nahed Ali, BA, Ahmed Elsayed, BA, Mahmoud M. Elsayed, MD; Magdi Ali, BA
MME Medical University, Mansoura, Egypt

Background
Wearable sensors have demonstrated remarkable potential in laboratory settings for quantifying upper limb recovery post-stroke, yet their translation to routine clinical practice remains limited. Despite robust validation studies showing high correlation with gold-standard measures (r>0.85), only 12% of rehabilitation centers have successfully integrated sensor-based assessments into standard care. This systematic review identifies the key barriers and facilitators in translating wearable sensor technologies from research to clinical implementation, focusing on practical considerations for therapists, healthcare systems, and patients.

Methods
We conducted a PRISMA-compliant review of PubMed, IEEE Xplore, and rehabilitation technology databases (2015-2024), including studies that: (1) implemented wearable sensors in clinical stroke rehabilitation settings, (2) reported on implementation challenges or success factors, and (3) provided quantitative clinical outcomes. Two reviewers independently extracted data on sensor types, clinical workflows, staff training requirements, and patient outcomes, assessing implementation quality using the Consolidated Framework for Implementation Research (CFIR).

Results
Analysis of 38 studies (n=2,417 patients) revealed three critical translation gaps: (1) 68% of systems required technical support unavailable in clinics, (2) 54% generated data too complex for clinical interpretation, and (3) 42% disrupted existing workflows. Successful implementations shared common features: simplified interfaces reducing setup time to <5 minutes (?=78% adoption rate), automated reports aligning with clinical scales (89% therapist satisfaction), and modular designs allowing gradual integration. Clinically, sensor-guided therapy groups showed 4.3-point greater FMA-UE improvements versus controls (p=0.008), with the largest effects in clinics using therapist-friendly visualization tools (?=5.1 points, p=0.003).

Conclusion
Effective translation of wearable sensors into clinical practice requires solutions that prioritize therapist needs alongside technological innovation. Key requirements include intuitive interfaces, clinically meaningful output metrics, and flexible implementation pathways. Future development must focus on creating rehabilitation-specific sensor systems designed with clinician input from the outset, rather than adapting research prototypes for clinical use.


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